Open-label study of COMP360 psilocybin therapy for

Professor Guy Goodwin, Chief Medical Officer, COMPASS Pathways, said: “These preliminary findings suggest COMP360 psilocybin therapy was well tolerated by cancer patients with major depressive disorder. It is promising to see that this may be a feasible fast-acting therapy for depressed patients with a significant physical co-morbidity. This would certainly be welcome in conditions where depression is difficult to treat in a timely way.”

These results are exciting especially when you’ve been told that you have treatment-resistant depression.

What I can say as a practicing Psychedelic Integration Therapist is that I have personally witnessed clients face, engage and participate in their lives more after consuming a microdose of psilocybin. Tracking the subtle shift in light, breath, and body sensations offers self agency. And when clients regulate their own regimen of amount and frequency of microdosing psychedelics, they are in the driver’s seat of their self-discovery.

Imagine that 1/10 of a gram of magic mushrooms ground up in a powder, literally a pinch!, when consumed can offer the slightest shift of perspective. Instead of drugging themselves, they consume a supplement. The mindset of self discovery rather than treatment sheds light on the resilience and vitality of the individual. Within the psychedelic context we expand the definition of wholeness and what is within our reach. Spirituality and Science intersect and then the human condition can be perceived with reverence and awe.

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  1. A new study that surveyed people at music festivals adds to the evidence that
    psychedelic drugs may improve mood and feelings of social connection, even after the drugs wear off.

    Experts say these drugs may hold some clues as to how to improve mood and possibly even combat mental health issues.

    The new research didn’t address whether there were negative effects from taking psychedelic drugs.

    Many people use psychedelic drugs to try to amplify the fun of a party or concert.

    Now a study published this week finds those drugs might keep the good vibes going even after the chemicals have worn off.

    Several past studies have found that in a laboratory setting, psychedelic drugs can help lessen anxiety, depression, or PTSD.

    The authors of the new study set out to try to find out whether these benefits to mood and mental health hold true in the real world.

    So, they went to places where people who use these drugs are likely to be: music festivals.

    After talking with more than 1,200 people at a half-dozen festivals, the researchers concluded that psychedelic drugs, such as LSD or “magic mushrooms,” left people feeling more socially connected and in a better mood, even after the drugs had worn off.

    These findings, the researchers said, confirm the previous laboratory research.

    The new findings add to the evidence that psychedelic drugs may hold some sort of clue to improving mood and possibly treating mental health issues.

    However, it may be a while, if ever, before we can make the connection and put the drugs to such uses.

    “Psychedelic research is still in its infancy,” Molly Crockett, PhD, the study’s senior author and an assistant professor of psychology at Yale University in Connecticut, told Healthline.

    “Our study adds to a growing evidence base of potential mood benefits of psychedelics, but more research needs to be done to realize this potential,” she said.

    What researchers discovered
    To help understand that potential, Crockett and her colleagues wanted to learn about the “afterglow” of psychedelics — how they affect someone after the drugs have worn off but while the person is still in the same setting where they were used.

    What they found was that people who had taken the drugs in the recent past — especially those who had taken them within the past 24 hours — were more likely to report “transformative experiences.”

    And these experiences were linked to feeling socially connected and being in a positive mood.

    Crockett notes there have been other studies that have surveyed people to try to understand how the drugs have affected mood months or years after they’ve used them.

    But, she said, “to our knowledge, ours is the first study to survey people’s experiences with psychedelics in a naturalistic setting immediately after their use.”

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